In the debate about the cognitive impacts of smartphones and digital technology a group reports that, contrary to widespread belief, scientific evidence doesn't show that these technologies harm biological cognitive abilities and that they instead only change predominant ways of cognition – such as a reduced need to remember facts or conduct mathematical calculations by pen and paper outside contemporary schools. However, some activities – like reading novels – that require long attention spans and don't feature ongoing rewarding stimulation may become more challenging in general.[2][3]
A study finds that ~9.4% of global deaths between 2000 and 2019 – ~5 million annually – can be attributed to extreme temperature with cold-related ones making up the larger share and decreasing and heat-related ones making up ~0.91 % and increasing.[4][5]
2 يوليو
The first scientific review in the professional academic literature about global plastic pollution in general finds that the rational response to the "global threat" would be "reductions in consumption of virgin plastic materials, along with internationally coordinated strategies for waste management" – such as banning export of plastic waste unless it leads to better recycling – and describes the state of knowledge about "poorly reversible" impacts.[6][7]
Researchers report that a mix of microorganisms from cow stomachs could break down three types of plastics.[8][9]
A preprint finds the SARS-CoV-2 Delta variant to cause a ~108 % increased – or more than twice as large – risk for hospitalization, a ~234 % increase for ICU admission and 132% for death compared to non-VOC variants.[16][17]
8 July – Scientists report that in the past – with little relevance to future evolution – lower temperatures were associated with larger Homo body sizes and that long-term variability in precipitation was correlated with brain size.[20][21]
10 July: Scientists report the discovery of long extrachromosomal DNA structures, they call "borgs", which appear to incorporate genes from organisms they encounter in or near archaea in mud.[22]
10 July – Scientists report in a preprint the discovery of long extrachromosomal DNA structures, they call borgs, which appear to incorporate genes from organisms they encounter. These structures, which could turn out to be an unknown form of giant viruses or "giant linear plasmids",[23][22] co-occur with a species of archaeon which may host them, shares many of their genes, whose main chromosome is only three times larger and whose capacity for anaerobic oxidation of methane as well as other biological functions – such as production of proteins – the borgs may augment.[24][25][22]
12 July – Scientists report in a preprint that the viral load in the first positive test of infections with the SARS-CoV-2 Delta variant was on average ∼1000 times higher than with compared infections during 2020.[26][27]
Researchers used a brain-computer interface to enable a man who was paralyzed since 2003 to produce comprehensible words and sentences by decoding signals from electrodes in the speech areas of his brain.[32][33]
Researchers describe effects of deforestation and climate change in a transformation of Amazonia from carbon sink to carbon source
Recently thought subglacial lakes under the Southern Polar cap of Mars based on a 2018 MARSIS measurement could also be clay minerals and frozen brine.[38][39]
A study concludes only 1.5-7 % of "regions"[مطلوب توضيح] of the modern human genome to be specific to modern humans. These regions have neither been altered by archaic hominin DNA due to admixture nor are shared with Neanderthals or Denisovans according to their used genomic datasets. They also found two bursts of changes specific to modern human genomes which involve genes related to brain development and function.[42][43]
A study using whole-genome resequencing indicates that Cannabissativa was first domesticated about 12,000 years ago in the early Neolithic period in East Asia, with the results being consistent with a single domestication origin.[44][45]
18 July – Journalists and researchers report the discovery of spyware, called "Pegasus", developed and distributed by a private company which can and has widely been used to infect iOS and Androidsmartphones often – partly based on 0-day exploits – without the need for any user-interaction or significant clues to the user and then be used to exfiltrate data, track user locations, capture film through its camera, and activate the microphone at any time.[46]
22 July: DeepMind's AlphaFold AI predicts the 3D structures of ~350,000 proteins.[47]
19 يوليو
Researchers review 217 analyses of on-the-market products and services as well as existing alternatives to mainstream food, holidays, and furnishings, and conclude that total greenhouse gas emissions by Swedes could be lowered by to date up to 36–38 % if consumers – without a decrease in total estimated expenditure or considerations of self-interest rationale – instead were to obtain those they could assess to be more sustainable.[48]
Scientists report that wild pigs are causing soil disturbance that, among other problems, globally results in annual carbon dioxide emissions equivalent to that of ~1.1 million passenger vehicles, implying that wild pig meat – unlike other meat products – has beneficial effects on the environment.[51][52]
28 July: The first direct observation of light from behind a black hole.[53]
DeepMind announces that its AlphaFold AI has predicted the structures of over 350,000 proteins, including 98.5% of the ~20,000 proteins in the human body. The 3D data along with their degrees of confidence for accuracy is made freely available with a new database, doubling the previous number of protein structures in the public domain.[47]
Scientists report to have created the first complete neuron-level-resolution 3D map of a monkey brain which they scanned within 100 hours.[66][67]
A study finds that the increasing probability of record week-long heat extremes occurrence depends on warming rate, rather than global warming level and provides projections.[68][69]
31 July – A kitchen robot – one of the first of its kind – for autonomous preparation of school meal program or delivery-service level amounts of discrete meals is demonstrated.[79]
أغسطس
9 August: The IPCC begins releasing its latest major report on climate change.
2 August – Engineers report the development of a prototype wave energy converter that is twice as efficient as similar existing experimental technologies, which could be a major step towards practical viability of tapping into the sustainable energy source.[80][81]
4 أغسطس
Scientists identify genetic determinants of ovarian ageing and possible effects of extending fertility in women.[82][83]
Scientists describe the molecular mechanisms by which insectolfactory systems are sensitive enough to recognize and discriminate a vast number of molecules with very few smell receptors.[84][85]
A study introduces an early-warning indicator for critical transitions of the Atlantic Meridional Overturning Circulation (AMOC) and finds early-warning signals in eight independent AMOC indices. A, possibly abrupt,[88] likely irreversible collapse from the current strong to a weak mode is thought to have severe impacts on Earth system components and global climate.[89][90] The Sixth IPCC report assesses a 'medium confidence' that such a collapse won't happen by 2100.[91]
8 August – The National Ignition Facility achieves a 70% yield, compared to the laser energy required to sustain fusion, from inertial confinementfusion energy, an 8X improvement over previous experiments in spring 2021 and a 25X increase over the yields achieved in 2018.[92]
A study based on OSIRIS-REx data concludes there to be a 1:1750 chance of an impact of asteroid (101955) Bennu by 2300, with the highest chance of impact being in 2182.[104][105]
22 August – Astronomers conclude in a preprint that – controversially due to there being only few data points – there is high confidence "Planet 9" exists, that it likely has a mass of ~6.2 Earths and is closer than thought previously and report its likely orbit.[126][127]
Cerebras announces a new hardware and software platform that can support AI models of 120 trillion parameters, enabling neural networks greater than the equivalent number of human brainsynapses.[128]
27 August – Scientists report about vaccine effectiveness, pandemic severity impacts and regional prevalence of SARS-CoV-2 Delta variant overall and its newly subdivided subvariants named from AY.1 onwards,[133] the first two of which were differentiated like so – also termed "Delta Plus" – in June.[134] On 10 August a preprint reports a case of asymptomatic transmissions associated with high viral load among vaccinated patients infected by AY.3.[135]
28 August – The world's northernmost island, a small patch of land measuring 60 x 30 metres, is reported by scientists off the coast of Greenland. The name Qeqertaq Avannarleq is proposed, which means "the northernmost island" in Greenlandic.[136]
Observation of a new class of supernova triggered by a black hole or neutron star crashing into the core of a companion star is reported by astronomers, based on studies of an extremely luminous source of radio waves called VT 1210+4956.[151][152][153]
A study finds that outdoor air pollution is associated with substantially increased mortality "even at low pollution levels below the current European and North American standards and WHO guideline values".[157][158] On 22 September, for the first time since 2005, the WHO, after a systematic review of the accumulated evidence, adjusted their air quality guidelines whose adherence could save millions of lives, protect against future diseases and help meet climate goals.[159][160]
Cysteamine, an antioxidant drug already approved for human use, is shown to reverse atherosclerosis, the process responsible for heart attacks and strokes, in mice.[171][172]
Scientists provide the first scientific assessment of the minimum amount of fossil fuels that would need to be securedfrom extraction per region as well as globally, to allow for a 50% probability of limiting global warming by 2050 to 1.5 °C.[173][174]
Scientists report that Earth is reflecting less light – a dimming of ~0.5% in reflectance over two decades may have both been co-caused by climate change as well as substantially increase global warming.[175][176]
10 سبتمبر
Scientists report what could be the discovery of the oldest rock art, likely dating back to ∼169–226,000 years ago, much older than what was previously thought to be the earliest known drawing, made ~73,000[177] years ago. Children likely intentionally placed a series of hands and feet in mud. The findings could also be the earliest evidence of Hominins on the above 4000 m a.s.l. high Tibetan plateau.[178][179][180]
43 expert scientists publish the first scientific framework version that – via integration, review, clarifications and standardization – enables the evaluation of levels of protection of marine protected areas and can serve as a guide for improving, planning and monitoring marine protection-quality and -extents such as in efforts towards the 30%-protection-goal of the "Global Deal For Nature"[181] and the UN's SDG 14.[182][183]
The CDC reports that despite prevalence of the Delta variant people vaccinated against COVID-19 are ~11 times less likely to die from COVID-19 (age-standardized rates of 1.6 versus 0.1 and 1.1 versus 0.1 weekly deaths per 100,000 U.S. citizens), showing vaccines' effectiveness at preventing severe disease.[184][185]
22 September: Astronomers report the discovery of the Per-Tau Shell, a giant star-forming spherical shell.24 September: Projecting effects of greenhouse gas emissions only for up to 2100 is found to be short-sighted. New models for climate change scenarios for up to 2500 are published.
13 September – A scientific review concludes that accumulating data suggests dietary restriction (DR) – mainly intermittent fasting and caloric restriction – results in many of the same beneficial changes in adult humans as in studied organisms, potentially increasing health- and lifespan.[186][187] A review published on 22 September provides an overview of DR as an intervention and develops a framework for a proposed field of "precision nutrigeroscience".[188][189] A study published on 29 September identifies circadian-regulatedautophagy as a critical contributor to intermittent time-restricted fasting-mediated lifespan extension in Drosophila and suggests that only certain forms of and/or combinations with intermittent fasting – intervals during which no food but only e.g. water and tea/coffee are ingested[190] – may be effective beyond the benefits of healthy body weight.[191][192]
Scientists confirm that widespread phytoplankton blooms can be a feedback effect of wildfires. The climate change-exacerbated 2019–2020 Australian wildfires caused oceanic deposition of wildfire aerosols, enhancing marine productivity and thereby increased oceanic carbon dioxide uptake.[196][197] A study using satellite data complements these findings, constraining the amount of CO2 emissions of the fires from November 2019 to January 2020 to around 715 million tons.[198][199]
16 September – Scientists report evidence of clothes being made 120,000 years ago based on findings in deposits in Morocco, a country in the northwestern part of Africa.[200][201]
Researchers report in a preprint the discovery of i.a. the so far closest known relative virus, with a 96.8% similarity, to SARS-CoV-2 in samples from wild horseshoe bats in northern Laos – 0.7% more similar than the virus RaTG13 discovered in China in 2013. Their findings indicate that, as of 2021, SARS-CoV-2-like viruses potentially infectious for humans circulate in bats in the Indochinese peninsula and that the pandemic virus may not originate from Wuhan.[204][205] Other scientists complement these findings, reporting in a preprint published on 20 September, that they could not find any SARS-CoV-2 related viruses in any samples collected in China, including from the only two domestic caves where RaTG13 and RmYN02 were detected, indicating such viruses may currently not circulate in bats in the country.[204][206]
22 September – Astronomers report the discovery of a nearby spherical structure, a 'superbubble', on the edges of which giant molecular clouds (Perseus and Taurus) with regions of star formation are being formed, the Per-Tau Shell.[207][208]
Media outlets report that the world's first synthetic coffee product has been created, still awaiting regulatory approval for near-term commercialization. On 15 September production of the first batches of synthetic coffee by another biotechnology company is reported.[211][212] Such products, for which multiple companies' R&D have acquired substantial funding, may have equal or highly similar effects, composition and taste as natural products but use less water, generate less carbon emissions, require less labor[بحاجة لمصادر إضافية] and cause no deforestation.[211]
Researchers report the world's first artificial synthesis of starch. The material essential for many products and the most common carbohydrate in human diets was made from CO2 in a cell-free process and could reduce land, pesticide and water use as well as greenhouse gas emissions while increasing food security.[213][214]
24 September: The first CRISPR-edited food, tomatoes, goes on public sale.28 September: Researchers develop machine learning models for genome-based early detection and prioritization of high-risk potential zoonotic viruses.
Media outlets report that in Japan the first CRISPR-edited food has gone on public sale. Tomatoes were genetically modified for around five times the normal amount of possibly calming[220]GABA.[221] CRISPR was first applied in tomatoes in 2014.[222]
26 September – Researchers estimate that children born in 2020 (e.g. "Generation Alpha") will experience 2–7 as many extreme weather events, particularly heat waves, compared to people born in 1960 (e.g. "Baby Boomers" and "Generation X") under current climate policy pledges over their lifetimes, raising issues of intergenerational equity.[225][226]
Pathogen researchers report the development of machine learning models for genome-based early detection and prioritization of high-risk potential zoonotic viruses in animals prior to spillover to humans. They conclude that their tool could be used for virus surveillance for pandemic prevention via (i.a.) measures of "early investigation and outbreak preparedness" and would have been capable of predicting SARS-CoV-2 as a high-risk strain.[233][234]
أكتوبر
1 October – A company conducting a preliminary small (~380 patients × 2) clinical trial launched a year ago[235] reports that molnupiravir substantially reduced the risk of hospitalization (7.3% to 14.1%) and death (8 to 0) from COVID-19.[236][237]
Metascientists report, based on a citation analysis, that "structures fostering disruptive scholarship and focusing attention on novel ideas" could be important as in a growing scientific fieldcitation flows disproportionately consolidate to citing already well-cited papers, possibly slowing and inhibiting canonical progress.[239][240]
The 2021 Nobel Prize in Chemistry is awarded to Benjamin List and David W.C. MacMillan for their work in creating a tool to build molecules, that may be useful for studies on developing new drugs and reducing the effect of chemicals on the environment.[242]
A study of data traffic by popular smartphones running variants of the Android software finds substantial by-default data collection and sharing with no opt-out and implications for users' privacy, control and security.[244][245]
8 October – A new eco-friendly way of extracting and separatingrare earth elements is described, using a bacteria-derived protein called lanmodulin, which binds easily to the metals.[251][252]
11 October: Scientists project public health impacts of an imminent Red Sea oil spill from the FSO Safer.
11 أكتوبر
Scientists report more precise dating of what appear to be the earliest bipedal footprints with hominin-like characteristics, the Trachilos footprints. They are found to be ~6.05 million years old, which is around the time of Orrorin – the previously earliest theorized species of Homininae[253] until these footprints were controversially dated in 2017,[254] despite being discovered outside of Africa in Crete, Greece. However, these apes are not necessarily associated with human evolution.[255][256][257]
The pilot project of the "world's first automated, driverless train" is launched in the city of Hamburg, Germany. The conventional, standard-track, non-metro train technology could theoretically be implemented for rail transport worldwide and is reported to also be substantially more energy efficient.[258][259]
Scientists project public health impacts, along with some of the environmental damage, of a, simulated, imminent Red Sea oil spill from the FSO Safer.[260][261]
20 October: Scientists report that, according to their genetic analysis, today's domestichorses descend from the lower Volga-Don region, Russia.
20 أكتوبر
Astronomers report the first evidence of a giant impact between two exoplanets, which occurred in the HD 172555 system, based on analysis of gas and dust concentrations.[276][277]
Scientists report that, according to their analysis, today's domestichorses descend from the lower Volga-Don region, Russia. 273 ancient horse genomes further indicate that these populations replaced almost all local populations as they expanded rapidly throughout Eurasia from about 4200 years ago, that certain adaptations were strongly selected for by horse riding, and that equestrian material culture – including Sintashta spoke-wheeled chariots and in the case of Asia Indo-Iranian languages – spread alongside.[278][279]
Medical researchers announce that on 25 September the first successful xenotransplantation of a, genetically engineered, pig kidney, along with the pig thymus gland to make the immune system recognize it as part of the body, to a brain-dead human with no immediate signs of rejection, moving the practice closer to clinical trials with living humans.[282][283]
Astronomers report, with two studies, that 'BLC1' does not appear to be a technosignature or extraterrestrial radio transmission because 15 similar observations were made between 2019 and 2020 that did not originate from around Proxima Centauri – and hence are likely results of forms of local radiofrequency interference – and propose a sequence of "verification checks for narrowband technosignature signals".[290][291][292]
Another, clearer case of quantum advantage with Zuchongzhi is reported.[293][294][295] A third study reported that Zuchongzhi 2.1 completed a task of classically simulating random circuit sampling that "is about 6 orders of magnitude more difficult than that of Sycamore".[296]
27 October: Researchers release a "policy sequencing" framework, in particular for policies of polycentric governance for completely halting and preventing deforestation.
Astronomers report that the orbits of the detected exoplanets hosted by the star HD 3167 are unusual: two planets (HD 3167 c; HD 3167 d) revolve around the poles of the star, whereas the third planet (HD 3167 b) orbits around the equator of the star instead.[299][300]
Researchers release a "policy sequencing" framework, in particular for policies of polycentric governance for completely halting and preventing deforestation based on data about already implemented government-designed policies, UN-decidedREDD+ initiatives and voluntary private sector initiatives of recent deforestation interventions.[301][302]
One year after India and South Africa called on WTO to temporarily waive TRIPS vaccine patents for accelerated deployment of COVID-19 vaccines around the world, the WTO reportedly fails to find an accord for doing so.[310] No mechanisms of alternative medical research and development incentive-systems[311] or technical details of proposed "sharing" after certain amounts of profit[312] were reported and some argue that, instead of intellectual property rights, manufacturing know-how is the main barrier to expanding capacity.[311]
Scientists discover that up to about 20,000 metric tons of microplastics may be stored in coral skeletons worldwide every year, marking the first time that a living microplastic "sink", or long-term storage site, has been quantified.[313]
2 November – A study concludes that PM2.5air pollution induced by contemporary forms of free trade and consumption by 19 G20 nations causes two million premature deaths annually, suggesting that the average lifetime consumption of about ~28 people in these countries causes at least one premature death (average age ~67) while developing countries "cannot be expected" to implement or be able to implement countermeasures without external support or internationally coordinated efforts.[318][319]
3 نوفمبر
Astronomers using the Atacama Large Millimeter/submillimeter Array (ALMA) report the presence of water in SPT0311-58, a galaxy nearly 12.9 billion light-years from Earth. This is the most distant detection of a required element for life in a regular star-forming galaxy.[320]
A study contributes to an entangling of the current geopolitical and economic implications of and incentives for a swift renewable energy transition, suggesting i.a. that how fast fossil energy markets decline is primarily decided by the major energy importers China, India, Japan and the EU and that transition dynamics may reverse the free-rider problem in the case of energy sectors, specifically from long-term strategic standpoints.[326][327]
Researchers demonstrate a novel X-ray imaging technique, "HiP-CT", for 3D cellular-resolution scans of whole organs, using the ESRF's EBF. The published online Human Organ Atlas includes the lungs from a donor who died with COVID-19.[328][329][330]
5 November – A company reports that a phase 2/3 clinical trial shows that PF-07321332 can reduce COVID-19 hospitalizations of high-risk adults by 89% when given within three days after symptom onset.[331][332]
8 November – Scientists prove that the brain (the insular cortex of mammals) also "remembers" immune activity against past infections, with reactivation – or stimulation – of the neurons being able to cause – or shape – the inflammatory immune response.[333][334]
9 نوفمبر
Astrophysicists report the discovery of unexplained blockage of high-energy cosmic rays entering the Galactic center, such as a strong magnetic field.[335][336]
Astronomers using the Very Large Telescope report the discovery of a black hole in NGC 1850 by viewing its influence on the motion of a star in close proximity, the first direct dynamical detection of a black hole in a young massive cluster.[340]
The first ever simulation of baryons on a quantum computer is reported by the University of Waterloo.[341]
Astronomers identify a long filament of cold, dense gas connecting two of the Milky Way's spiral arms, the first known observation of such a galactic structure in the Milky Way.[342]
Bionanoengineers report a novel therapy for spinal cord injury – an injectable gel of nanofibers that contain moving molecules that cause cellular signaling and mimic the matrix around cells in mice.[343][344][345]
A study investigates how tidal energy could be best integrated into the Orkneyenergy system.[346] On 3 November, a review assesses the potential of tidal energy in the UK's energy systems, finding it could deliver 34 TWh/y or 11% of the energy demand.[347][348]
14 November – A time-allocation study estimates that in 2020 over 130 million hours of researchers' time were spent on peer review.[349][350]
14 November – Scientists report a large extent of alternative splicing – cases of a single gene (a template) being used to create instructions (mRNAs) for building different proteins – in the mouse and human cortex and release the transcriptomes on a public database.[351][352]
A systematic review and meta analysis finds that mask wearing cuts the incidence of COVID-19 by 53%.[356]
The first 256-qubitquantum computer is announced, by startup company QuEra, founded by MIT and Harvard scientists and funded by DARPA.[357][358]
The largest public dataset of whole genomes is made available through a Web platform. The entire genomes of 200,000 UK Biobank participants, linked to anonymized medical information, are made more accessible for biomedical research than prior, less comprehensive datasets.[359][360]
Scientists call for the creation of space biosecurity measures and inform the creation of planetary protection policies that aim to prevent forward contamination of extraterrestrial bodies as well as backward contamination.[361][362]
Scientists report the development of a vaccine of mRNAs for the body build 19 proteins in tick saliva which, by enabling quick development of erythema (itchy redness) at the bite site, protects guinea pigs against Lyme disease from ticks.[363][364]
21 November – Sri Lanka announces that it will lift its import ban on pesticides and herbicides, explained by both a lack of sudden changes to widely applied practices or education systems and contemporary economics and, by extension, food security, protests and food costs. The effort to become the world's first completely organic farming nation was challenged by effects from the COVID-19 pandemic.[366][367]
22 November – Scientists detect a quantum effect that blocks atoms from scattering light.[368]
25 November – Researchers systematically assess impacts of climate change mitigation options on 18 constituents of well-being, finding largely beneficial effects of demand-side solutions based on inputs from 604 studies.[370][371]
26 November – The WHO announces the classification of the Omicron variant as a SARS-CoV-2 variant of concern. The variant, that became dominant (74% of samples) in South Africa in November, was detected by the NGS-SA genomic surveillance on 8 November[372][373] and reported to the WHO on 24 November.[355] It has a large number of mutations that, according to early preliminary evidence, appear to increase risk of reinfection,[355] may possibly increase transmissibility compared to Delta and may affect vaccines' efficacies with a key question being whether it causes less severe prognoses.[374][375]
29 November – A team of scientists publish a new form of biological reproduction in xenobots.[376]
ديسمبر
1 December – Scientists discover the footprint of an ancient hominid that lived alongside Lucy.[377]
3 ديسمبر - لأول مرة، حقق تفاعل اندماج، رقمأً قياسياً من الطاقة الناتجة، 1.3 1.3 ميگاجول، متجاوزاً الطاقة التي يمتصها الوقود المستخدم لتشغيله، الذي يعد اختراقاً في سعي العلماء للحصول على طاقة الاندماج. وتمثل الطاقة الناتجة، ثمانية أضعاف ما تم الحصول عليه في التجارب السابقة، التي أُجريت قبل بضعة أشهر فقط، و25 ضعف ما أنتجته التجارب التي أُجريت عام 2018.[380]
7 December – A study in PNAS finds that when two people wear surgical masks, while the infectious is speaking, the risk of COVID-19 infection remains below 30% after one hour, but when both wear a well-fitting FFP2 mask, it is 0.4%.[382]
Plan S, an initiative for open-accessscience publishing launched in 2018,[392][393] requires that from 2021 papers from over 10 European countries that resulted from research funded by public grants must be published under an open licence in compliant journals or platforms, available to all.[394][395]
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